Practical research guides
Original educational content with official sources. Medical review pending.
How to explore participation in a clinical study
A practical starting point for people considering research in Hialeah.
Read the guide →Preparing for your first research visit
Questions and practical arrangements to discuss before traveling.
Read the guide →Evaluating a research site: a sponsor conversation checklist
An IHR planning checklist to support protocol-specific feasibility discussions.
Read the guide →Clinical trial consent: questions to ask before deciding
A practical question list for prospective participants in Hialeah and South Florida.
Read the guide →Clinical research referrals in Hialeah: how physicians can contact IHR
A clear starting point for physicians and care teams exploring research options.
Read the guide →Research worth reading.
A curated selection from established medical journals. Explore clinical findings, research methods, and perspectives on the future of medical research.
Selection reviewed: October 10, 2026 · Publication years shown on each article.
CONSORT 2025: clearer reporting of clinical trials
Updated recommendations help authors explain how randomized trials were conducted and what they found. The guidance supports transparent reporting so readers can evaluate the evidence.
A reporting guideline does not establish the efficacy of a treatment.
Publication reference
CONSORT 2025 statement: updated guideline for reporting randomised trials
DOI: 10.1136/bmj-2024-081123
AI-assisted drug discovery reaches a lung fibrosis trial
A 71-person, 12-week trial evaluated rentosertib, developed using generative AI, in idiopathic pulmonary fibrosis. Safety was the primary endpoint; lung-function findings supported further investigation.
Small, short-duration study; larger trials are needed to establish clinical benefit.
Publication reference
A generative AI-discovered TNIK inhibitor for idiopathic pulmonary fibrosis: a randomized phase 2a trial
DOI: 10.1038/s41591-025-03743-2
Semaglutide and obesity-related heart failure
A prespecified pooled analysis of two trials compared semaglutide with placebo in obesity-related heart failure with preserved ejection fraction. The treatment improved symptoms and physical limitations and reduced body weight in the studied population.
Findings should not be generalized to every form of heart failure.
Publication reference
STEP-HFpEF and STEP-HFpEF DM: pooled analysis
DOI: 10.1016/S0140-6736(24)00469-0
Diversity among trial participants and research leaders
This commentary addresses diversity across clinical-trial participation and leadership. It offers a perspective on representation in the research enterprise.
Commentary, rather than a randomized test of an intervention.
Publication reference
Why diversity is needed at every level of clinical trials, from participants to leaders
DOI: 10.1038/s41591-024-02914-x
SELECT: cardiovascular outcomes in obesity without diabetes
In people with established cardiovascular disease and overweight or obesity but without diabetes, SELECT found fewer major cardiovascular events with semaglutide than placebo. The trial examined cardiovascular outcomes in a defined high-risk population.
Results apply to the trial population; individual treatment requires medical evaluation.
Publication reference
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
DOI: 10.1056/NEJMoa2307563
SPRINT MIND: blood pressure and cognitive outcomes
Intensive blood-pressure control reduced mild cognitive impairment in this trial but did not significantly reduce probable dementia. The findings illustrate why primary and secondary outcomes must be interpreted separately.
Early trial termination and fewer dementia cases limited the dementia analysis.
Publication reference
Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial
DOI: 10.1001/jama.2018.21442
No articles match these filters. Try another topic or clear your search.
Educational summaries prepared for this website. These are external publications, not studies advertised as recruiting at Integrated Health Research. They do not replace medical advice or indicate endorsement by the journals. Publisher access terms may apply to the original articles.
External publications are provided for reading and do not represent studies conducted at IHR or endorsements of this site. Publisher access restrictions may apply. Educational content should not replace medical advice.